Asimul Islam | Biochemistry | Lifetime achievement Award

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Prof Dr. Asimul Islam | Biochemistry | Lifetime achievement Award

Jamia Millia Islamia (a Central University), India

Author Profile

Early Academic Pursuits 📚

Dr. Asimul Islam’s academic journey reflects his dedication to biosciences, with a foundation laid in Jamia Millia Islamia (JMI) and Cambrian Hall School. Completing his B.Sc. in Biosciences with First Division in 1999 from JMI, he moved to an M.Sc. in Biosciences from the same university, also graduating with distinction in 2001. His M.Sc. dissertation, which focused on PCR amplification of the chr A gene from Indian isolates of E. coli, marked the beginning of his focus on molecular biology and bioinformatics. Dr. Islam’s formative years were enriched at Cambrian Hall School, where he consistently achieved high honors, earning distinctions in multiple subjects, a foundation that set the stage for his exceptional career in biosciences.Dr. Islam’s Ph.D., completed at JMI, further showcased his growing expertise in biophysics and biochemistry. His doctoral work, “Studies of Conformation and Conformational Stability of Nef Protein of HIV-1,” explored protein structure and stability—a critical area in understanding HIV biology and treatment. This phase allowed Dr. Islam to develop technical acumen and establish a research foundation that continues to influence his work in molecular biophysics.

Professional Endeavors and Leadership 🔬

As a professor at JMI, Dr. Islam brings over 17 years of teaching experience across a wide spectrum of courses, including interdisciplinary sciences, biotechnology, bioinformatics, and biophysics. His diverse teaching portfolio spans course work at all levels—from Ph.D. and M.Phil. programs to the ten semesters of the integrated M.Sc. programs. This extensive involvement has allowed Dr. Islam to shape the academic trajectories of numerous students, emphasizing critical scientific approaches and hands-on research skills.Dr. Islam has made significant contributions as a Co-Ordinator of Extension Activities at the Centre for Interdisciplinary Research in Basic Sciences, JMI, organizing multiple initiatives aimed at engaging the community and fostering scientific collaboration. His role in JMI’s Institutional Animal Ethics Committee also reflects his commitment to ethical scientific practices and the responsible use of animal models in research, a critical element of modern biosciences.

Contributions and Research Focus 🌐

Dr. Islam’s research is marked by extensive contributions in protein biophysics, structural biology, and molecular biosciences. With over 280 peer-reviewed publications, his research covers various topics, including protein conformational studies, peptide stability, and biophysical interactions—areas essential to understanding disease mechanisms and potential therapeutic avenues. His work on HIV-1 Nef protein conformation, for instance, has been instrumental in uncovering structural insights with potential implications for HIV research.Over the years, Dr. Islam has successfully led six major research projects funded by prestigious Indian science agencies, including DST-SERB, DBT, CSIR, and UGC. His ongoing projects further expand his contributions to biochemistry, involving areas that are central to developing treatments for complex diseases. His mentorship extends to 8 Ph.D. students currently enrolled under him, along with another 12 working under his co-supervision. To date, Dr. Islam has supervised over 100 M.Sc. dissertations and summer training projects, providing a critical learning ground for students to gain practical research experience.

Accolades and Recognition 🏆

Dr. Islam’s scientific achievements and professional dedication have earned him a place in the National Academy of Sciences, India (NASI), one of the country’s most prestigious scientific organizations. He is also a life member of various national and international scientific bodies, including the Iranian Society of Biophysical Chemistry (ISOBC), Indian Immunology Society, and Society of Biological Chemists. His active engagement in these bodies reflects his contributions to the broader scientific community, where he regularly collaborates and shares his expertise.Dr. Islam has published abstracts in more than 50 conferences, delivering invited talks at premier institutions, both in India and abroad. His role as a coordinator in organizing national and international conferences at JMI, including the National Symposium on Biophysics and the Golden Jubilee Meeting of the Indian Biophysical Society, has further cemented his reputation as a leader in his field. His organization of two three-week Refresher Courses in Basic Sciences has contributed significantly to faculty development and academic excellence.

Impact and Influence 🌍

Dr. Islam’s work has had a substantial impact on the academic and research communities. His dedication to training and mentorship has influenced generations of students, many of whom have continued to contribute to the biosciences in their careers. His ability to foster interdisciplinary collaboration has also led to innovative approaches and novel insights within molecular biophysics and structural biology.Beyond academia, Dr. Islam’s research on protein structure and stability, especially his work with HIV-1, contributes to fields with direct implications for health and medical research. His extensive publication record and active engagement in scientific societies exemplify his commitment to advancing biosciences, promoting rigorous scientific standards, and encouraging collaborative research.

Legacy and Future Contributions 🚀

Dr. Asimul Islam’s legacy is rooted in his commitment to teaching, his vast research output, and his leadership within academic and scientific communities. His influence extends beyond JMI, impacting the broader bioscience field through his contributions to structural biology and his involvement in professional organizations. Looking forward, Dr. Islam aims to expand his research portfolio and continue to train and mentor the next generation of scientists.With a strong foundation in interdisciplinary sciences and a passion for advancing molecular biosciences, Dr. Islam is well-positioned to leave a lasting legacy. His future endeavors will likely focus on groundbreaking research projects, contributing to advancements in biophysics, bioinformatics, and disease research—areas that will benefit from his vast expertise and dedication to scientific exploration. Through his enduring contributions, Dr. Islam continues to inspire a legacy of innovation and excellence in biosciences.

Citations

A total of 6455 citations for his publications, demonstrating the impact and recognition of his research within the academic community.

  • Citations        6455
  • h-index          278
  • i10-index       43

Notable Publications 

  • Title: Recent advancement in understanding of Alzheimer’s disease: Risk factors, subtypes, and drug targets and potential therapeutics
    Authors: Prabha, S.; Sajad, M.; Hasan, G.M.; … Imtaiyaz Hassan, M.; Thakur, S.C.
    Journal: Ageing Research Reviews
    Year: 2024.
  • Title: Targeting prostate cancer via therapeutic targeting of PIM-1 kinase by Naringenin and Quercetin
    Authors: Rathi, A.; Chaudhury, A.; Anjum, F.; … Hassan, M.I.; Haque, M.M.
    Journal: International Journal of Biological Macromolecules
    Year: 2024.
  • Title: Navigating the Maze of Alzheimer’s disease by exploring BACE1: Discovery, current scenario, and future prospects
    Authors: Iram, F.; Shahid, M.; Ansari, J.; … Hassan, M.I.; Islam, A.
    Journal: Ageing Research Reviews
    Year: 2024.
  • Title: Improving faster R-CNN generalization for intestinal parasite detection using cycle-GAN based data augmentation
    Authors: Kumar, S.; Arif, T.; Ahamad, G.; … Ali, M.A.M.; Islam, A.
    Journal: Discover Applied Sciences
    Year: 2024.
  • Title: Probing protein aggregation through spectroscopic insights and multimodal approaches: A comprehensive review for counteracting neurodegenerative disorders
    Authors: Bashir, S.; Aiman, A.; Chaudhary, A.A.; … Hassan, M.I.; Islam, A.
    Journal: Heliyon
    Year: 2024.

Akhilesh kumar Kuril | Biochemistry | Research Excellence Award

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Mr. Akhilesh kumar Kuril | Biochemistry | Research Excellence Award

Bhagwant university, Ajmer, India

Author Profile

🎓 Early Academic Pursuits

Akhilesh Kumar Kuril’s journey into the world of pharmaceutical sciences began with a strong academic foundation. Born on June 8, 1986, in India, Akhilesh demonstrated a keen interest in chemistry and pharmaceutical sciences early in life. His academic pursuit started with a Bachelor of Pharmacy (B. Pharm) from Ram-Eesh Institute of Vocational & Technical Education in Greater Noida, Uttar Pradesh. This institution is affiliated with the Abdul Kalam Technical University, formerly Uttar Pradesh Technical University (UPTU), Lucknow. Akhilesh completed his B. Pharm between 2005 and 2009, securing an impressive 71.0% marks. This early success laid the groundwork for his future achievements in pharmaceutical chemistry.He continued his academic journey by pursuing a Master of Pharmacy (M. Pharm) in Pharmaceutical Chemistry from Babu Banarasi Das National Institute of Technology & Management, Lucknow. This institution, also affiliated with Abdul Kalam Technical University, provided him with the platform to delve deeper into pharmaceutical sciences. Between 2009 and 2011, Akhilesh excelled in his M. Pharm studies, achieving 76.0% marks. His dedication and hard work during these formative years were evident, and they set the stage for his future contributions to the field.

💼 Professional Endeavors

Akhilesh’s professional career is marked by his extensive experience as an analytical scientist. With over 12 years of experience in the analytical research and development of drug substances, both small and large molecules, and drug products such as peptides, proteins, injectables, ophthalmic, and oral solid dosage forms, Akhilesh has established himself as a key figure in the pharmaceutical industry. Currently, he holds the position of Chemist II, QC at Ambiopharm Inc., located in North Augusta, South Carolina, USA.In his role, Akhilesh is responsible for the characterization study and developmental studies for drug product analytical method validation and troubleshooting. His expertise in responding to deficiencies received from regulatory agencies highlights his critical role in ensuring that pharmaceutical products meet stringent regulatory standards. Akhilesh’s proficiency in various analytical techniques, including chromatographic techniques such as Reverse Phase (RP), Ion Pair (IP), Ion Exchange Chromatography (IEX), and Size Exclusion Chromatography (SEC), coupled with different detectors like UV, RI, Fluorescence, MALS, and MS, underscores his technical prowess.

🔬 Contributions and Research Focus

Akhilesh’s contributions to the field of pharmaceutical analysis are substantial. His research focus extends to peptide characterization techniques, including Circular Dichroism, Fluorescence Spectrometry, UHPLC-HRMS (Top-down and Bottom-up MS), Dynamic Light Scattering (DLS), SV-AUC, and CE. Additionally, he is well-versed in solid-state characterization techniques such as Particle Size Analysis, PXRD, DSC, and TGA. These techniques are critical in ensuring the quality, efficacy, and safety of pharmaceutical products.His work in method development, validation, and regular analysis using high-performance instruments like HPLC, UPLC, and UHPLC-HRMS has been instrumental in advancing the field of pharmaceutical analysis. Akhilesh’s ability to apply bioinformatics tools for protein mapping and amino acid sequencing further enhances the precision and reliability of his research.

🏆 Accolades and Recognition

Akhilesh’s dedication to excellence in his field is reflected in the numerous certifications and recognitions he has received. In August 2021, he earned Green Belt and Black Belt Certifications in Lean Six Sigma with a Seal of Excellence from Exemplar Global and Benchmark Six Sigma. These certifications demonstrate his commitment to continuous improvement and operational excellence. In September 2021, he furthered his credentials by receiving a Certificate in Excellence in Continuous Improvement Leadership (ECIL) from Benchmark Six Sigma.These accolades not only recognize Akhilesh’s expertise in pharmaceutical analysis but also highlight his leadership abilities in driving efficiency and quality in pharmaceutical research and development.

🌍 Impact and Influence

Akhilesh’s impact on the pharmaceutical industry is profound. His work at Ambiopharm Inc. and previous roles has contributed significantly to the development and validation of methods that ensure the safety and efficacy of pharmaceutical products. His expertise in handling complex regulatory challenges and his ability to troubleshoot analytical methods have made him a valuable asset to his organization and the industry at large.Moreover, Akhilesh’s research in peptide and protein characterization techniques has influenced the way these essential biomolecules are analyzed, leading to more accurate and reliable results. His contributions are particularly important in the context of developing generic peptide products, where precise characterization is critical to ensuring bioequivalence and safety.

👨‍💻 Legacy and Future Contributions

Looking ahead, Akhilesh Kumar Kuril’s legacy in the pharmaceutical industry is poised to grow even further. As he continues to pursue his Ph.D. in Pharmaceutical Analysis from Bhagwant University, Rajasthan, India, Akhilesh is on track to make even more significant contributions to the field. With his thesis already submitted and his graduation anticipated in 2024, Akhilesh’s research and findings are expected to add valuable knowledge to the field of pharmaceutical analysis.Akhilesh’s future contributions will likely focus on advancing analytical techniques and developing innovative methods for drug substance and product characterization. His ongoing commitment to excellence, continuous improvement, and innovation ensures that he will remain at the forefront of the pharmaceutical industry, driving advancements that benefit both the industry and patients worldwide.

Notable Publications 

  • Title: Analytical considerations for characterization of generic peptide product: A regulatory insight
    Authors: Kuril, A.K., Saravanan, K., Subbappa, P.K.
    Journal: Analytical Biochemistry
    Year: 2024.
  • Title: High-throughput method for Peptide mapping and Amino acid sequencing for Calcitonin Salmon in Calcitonin Salmon injection using Ultra High Performance Liquid Chromatography – High Resolution Mass Spectrometry (UHPLC-HRMS) with the application of Bioinformatic tools
    Authors: Kuril, A.K., Saravanan, K.
    Journal: Journal of Pharmaceutical and Biomedical Analysis
    Year: 2024.
  • Title: A comprehensive guide for secondary structure and tertiary structure determination in peptides and proteins by circular dichroism spectrometer
    Authors: Kuril, A.K., Vashi, A., Subbappa, P.K.
    Journal: Journal of Peptide Science
    Year: 2024.

OWAIS BHAT | Biochemistry | Best Researcher Award

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Assist Prof Dr. OWAIS BHAT | Biochemistry | Best Researcher Award

Central University of Kashmir- India

Author Profile

🧑‍🎓Early Academic Pursuits 

Dr. Owais Mohmad Bhat, M.Sc., Ph.D., began his illustrious academic journey in the picturesque region of Kashmir, India. His passion for life sciences led him to pursue a B.Sc. in Biochemistry, Chemistry, and Zoology from Sri Pratap College, affiliated with the University of Kashmir. During this period, he developed a strong foundation in the biological sciences, which would later be crucial in his research pursuits.Following his undergraduate studies, Dr. Bhat continued his academic journey at the University of Kashmir, where he completed his M.Sc. in Biochemistry from 2005 to 2007. This period was marked by his growing interest in molecular biology and biochemistry, particularly in understanding the biochemical mechanisms underlying various physiological and pathological processes.His academic pursuits eventually led him to one of the most prestigious institutions in India, the Postgraduate Institute of Medical Education and Research (PGIMER) in Chandigarh. Here, Dr. Bhat embarked on his Ph.D. journey in Biochemistry under the guidance of eminent professors, including Prof. Veena Dhawan, Prof. Deepak Kaul, and Dr. N.V. Giridharan. His thesis, titled “To Study the Effect of Terminalia Arjuna on Interleukin-18 Induced Modulation of Peroxisome Proliferator Activated Receptor-γ Transcriptome in Apo E -/- Mice Model of Atherosclerosis,” explored the molecular mechanisms involved in cardiovascular diseases, particularly atherosclerosis, and the potential therapeutic effects of natural compounds.

🧪Professional Endeavors and Research Focus

Dr. Owais Mohmad Bhat’s professional journey is characterized by his dedication to understanding complex biochemical pathways and their implications in human health and disease. After completing his Ph.D., he moved to the United States, where he worked as a Post-Doctoral Researcher in the Department of Comparative Biomedical Sciences at Louisiana State University. Under the mentorship of Professor Yogesh Saini, Dr. Bhat’s research focused on the role of macrophages in respiratory diseases, particularly the impact of altered macrophage populations on immune responses in respiratory airspaces.In 2016, Dr. Bhat joined the Department of Pharmacology and Toxicology at Virginia Commonwealth University as a Post-Doctoral Researcher. Here, he worked under the supervision of Professor Pin-Lan Li, where he delved into the regulation of autophagic flux by lysosome-associated signaling pathways. His research uncovered critical insights into how deficient autophagy in coronary arterial smooth muscle cells (CASMCs) could lead to atherosclerosis, with a particular focus on the role of lysosomal dysfunction in vascular calcification.ince December 2021, Dr. Bhat has been serving as a Scientist-D and Ramalingaswami Fellow at the Department of Biotechnology, School of Life Sciences, Central University of Kashmir. His current research focuses on vascular calcification, particularly the formation and accumulation of calcium phosphate salts within the vascular wall, which is associated with aging, chronic kidney disease, diabetes mellitus, and atherosclerosis. His work explores the role of small membrane-bound bodies, known as matrix vesicles (MVs), and their exosome counterparts in nucleating calcium phosphate crystals, leading to vascular calcification.

🧬Contributions and Research Focus

Dr. Bhat’s research has significantly contributed to our understanding of the molecular mechanisms underlying vascular calcification. His work has demonstrated how lysosomal dysfunction and sphingolipid metabolism play a crucial role in the excretion of exosomes from arterial smooth muscle cells (SMCs), ultimately leading to vascular calcification. His research also highlights the potential therapeutic targets within the mammalian target of rapamycin complex (mTORC) signaling pathways, which could be manipulated to prevent or reverse vascular calcification.In addition to his research on vascular calcification, Dr. Bhat has also contributed to the field of cardiovascular diseases through his studies on the role of sphingolipids, ceramide, and sphingosine-1-phosphate (S1P) in regulating autophagy and exosome secretion. His research has opened new avenues for understanding how these molecules influence the development of calcification in atherosclerotic plaques and arterial walls.

🏆Accolades and Recognition

Dr. Owais Mohmad Bhat’s dedication to his research has not gone unnoticed. He has been awarded the prestigious Ramalingaswami Fellowship by the Department of Biotechnology, Government of India, which recognizes outstanding scientists returning to India to contribute to the country’s scientific research landscape. This fellowship has allowed Dr. Bhat to continue his groundbreaking research at the Central University of Kashmir, where he has secured funding of 113.6 Lakhs for his projects.

🌍Impact and Influence

Dr. Bhat’s work has had a profound impact on the scientific community’s understanding of vascular calcification and its underlying mechanisms. His research has provided valuable insights into potential therapeutic targets for preventing or treating cardiovascular diseases, particularly in populations at high risk, such as those with chronic kidney disease or diabetes.Moreover, as a mentor to four Ph.D. scholars, Dr. Bhat is actively contributing to the next generation of scientists. His guidance and expertise are helping shape the future of biochemistry and molecular biology research in India.

🌟Legacy and Future Contributions

Dr. Owais Mohmad Bhat’s research legacy is one of dedication to unraveling the complexities of human health and disease at the molecular level. His work on vascular calcification and the role of sphingolipids in cardiovascular diseases is paving the way for new therapeutic approaches that could significantly impact public health.As he continues his research at the Central University of Kashmir, Dr. Bhat is poised to make even more significant contributions to the field. His future work is expected to delve deeper into the molecular mechanisms of vascular calcification, potentially leading to new treatments that could prevent the progression of atherosclerosis and other related diseases.In summary, Dr. Owais Mohmad Bhat, M.Sc., Ph.D., is a distinguished scientist whose work is making a lasting impact on the field of biochemistry and molecular biology. His research, mentorship, and dedication to advancing scientific knowledge are contributing to a brighter future for cardiovascular disease treatment and prevention.

Citations

A total of 751 citations for his publications, demonstrating the impact and recognition of his research within the academic community.

  • Citations         751
  • h-index           35
  • i10-index        17

Notable Publications 

  • Title: Contribution of Hepatic Steatosis–Intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice
    Authors: Yuan, X., Bhat, O.M., Zou, Y., Zhang, Y., Li, P.-L.
    Journal: American Journal of Pathology
    Year: 2023
  • Title: A Review on Anti-Nutritional Factors: Unraveling the Natural Gateways to Human Health
    Authors: Salim, R., Nehvi, I.B., Mir, R.A., Ali, S., Bhat, O.M.
    Journal: Frontiers in Nutrition
    Year: 2023
  • Title: Endothelial Acid Sphingomyelinase Promotes NLRP3 Inflammasome and Neointima Formation during Hypercholesterolemia
    Authors: Yuan, X., Bhat, O.M., Zou, Y., Zhang, Y., Li, P.-L.
    Journal: Journal of Lipid Research
    Year: 2022
  • Title: Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus
    Authors: Chen, Y., Li, G., Bhat, O.M., Zhang, Y., Li, P.-L.
    Journal: Frontiers in Physiology
    Year: 2022
  • Title: Exosome Biogenesis and Lysosome Function Determine Podocyte Exosome Release and Glomerular Inflammatory Response during Hyperhomocysteinemia
    Authors: Huang, D., Li, G., Bhat, O.M., Ritter, J.K., Li, P.-L.
    Journal: American Journal of Pathology
    Year: 2022.

Rajasekaran Chandrasekaran | Plant Physiology | Best Research Award

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Prof. Rajasekaran Chandrasekaran - Plant Physiology - Best Research Award 🏆

Vellore Institute of Technology - India

Professional Profiles

Early Academic Pursuits

His academic journey commenced with a strong foundation in science at G.H.M.H.S. School, Salem, where he completed his S.S.L.C. Following this, he pursued his Higher Secondary education at L.F.H.S. School, Salem, specializing in Physics, Chemistry, Botany, and Zoology. His passion for botanical sciences led him to pursue a Bachelor's degree in Botany at Govt. Arts College, Salem, affiliated with the University of Madras. Subsequently, he furthered his academic pursuits with a Master's degree in Botany from Annamalai University. Driven by a quest for deeper knowledge in plant physiology, he pursued a D.Phil. at H.N.B. Garhwal University, focusing on the changes in enzyme activity of ammonium assimilation in plants across altitudinal gradients.

Professional Endeavors

His professional journey is marked by a remarkable blend of academic excellence and research contributions. He has held several prestigious positions in academia and research, including serving as a Research Associate at the Department of Biotechnology, Government of India, and as a faculty member at various educational institutions. His expertise in plant physiology has been instrumental in shaping the curriculum and research agendas in the field. Additionally, his affiliations with renowned scientific organizations and networks have facilitated collaborations and knowledge exchange on a global scale.

Contributions and Research Focus in Plant Physiology

His research endeavors have revolved around elucidating the intricate mechanisms governing plant physiology, with a particular emphasis on photosynthesis, transpiration, hormonal regulation, and nutrient uptake. His pioneering work has contributed significantly to our understanding of plant responses to environmental cues and stressors. Through meticulous experimentation and scholarly inquiry, he has uncovered novel insights into the physiological processes underlying plant growth, development, and adaptation. Plant physiology is the branch of biology that focuses on understanding the functioning and processes of plants at the cellular, tissue, and whole-organism levels. It encompasses a wide range of topics, including photosynthesis, transpiration, hormonal regulation, and nutrient uptake, among others.

Accolades and Recognition

His outstanding contributions to the field of plant physiology have earned him widespread recognition and numerous accolades. His research excellence has been acknowledged through prestigious awards such as the Best Research Award, bestowed upon him in recognition of his groundbreaking contributions to the field. Furthermore, his affiliations with esteemed scientific societies and organizations reflect his stature as a respected figure in the scientific community.

Impact and Influence

His work has left a lasting impact on the field of plant physiology, inspiring fellow researchers and shaping the trajectory of scientific inquiry. His findings have practical implications for agricultural practices, environmental conservation, and sustainable development. By elucidating the fundamental principles governing plant physiology, he has paved the way for innovative approaches to address global challenges such as food security and climate change.

Legacy and Future Contributions

Looking ahead, he remains committed to advancing the frontiers of plant physiology through continued research, mentorship, and advocacy. His legacy is defined by his unwavering dedication to scientific inquiry and his profound influence on the next generation of scientists. As he continues to champion excellence in plant physiology, his contributions will undoubtedly shape the future of agricultural science and environmental stewardship for generations to come.

Citations

  • Citations               1777
  • h-index                   26
  • i10-index                50

Notable Publications