Mr. Akhilesh kumar Kuril | Biochemistry | Research Excellence Award

Bhagwant university, Ajmer, India

Author Profile

🎓 Early Academic Pursuits

Akhilesh Kumar Kuril’s journey into the world of pharmaceutical sciences began with a strong academic foundation. Born on June 8, 1986, in India, Akhilesh demonstrated a keen interest in chemistry and pharmaceutical sciences early in life. His academic pursuit started with a Bachelor of Pharmacy (B. Pharm) from Ram-Eesh Institute of Vocational & Technical Education in Greater Noida, Uttar Pradesh. This institution is affiliated with the Abdul Kalam Technical University, formerly Uttar Pradesh Technical University (UPTU), Lucknow. Akhilesh completed his B. Pharm between 2005 and 2009, securing an impressive 71.0% marks. This early success laid the groundwork for his future achievements in pharmaceutical chemistry.He continued his academic journey by pursuing a Master of Pharmacy (M. Pharm) in Pharmaceutical Chemistry from Babu Banarasi Das National Institute of Technology & Management, Lucknow. This institution, also affiliated with Abdul Kalam Technical University, provided him with the platform to delve deeper into pharmaceutical sciences. Between 2009 and 2011, Akhilesh excelled in his M. Pharm studies, achieving 76.0% marks. His dedication and hard work during these formative years were evident, and they set the stage for his future contributions to the field.

💼 Professional Endeavors

Akhilesh’s professional career is marked by his extensive experience as an analytical scientist. With over 12 years of experience in the analytical research and development of drug substances, both small and large molecules, and drug products such as peptides, proteins, injectables, ophthalmic, and oral solid dosage forms, Akhilesh has established himself as a key figure in the pharmaceutical industry. Currently, he holds the position of Chemist II, QC at Ambiopharm Inc., located in North Augusta, South Carolina, USA.In his role, Akhilesh is responsible for the characterization study and developmental studies for drug product analytical method validation and troubleshooting. His expertise in responding to deficiencies received from regulatory agencies highlights his critical role in ensuring that pharmaceutical products meet stringent regulatory standards. Akhilesh’s proficiency in various analytical techniques, including chromatographic techniques such as Reverse Phase (RP), Ion Pair (IP), Ion Exchange Chromatography (IEX), and Size Exclusion Chromatography (SEC), coupled with different detectors like UV, RI, Fluorescence, MALS, and MS, underscores his technical prowess.

🔬 Contributions and Research Focus

Akhilesh’s contributions to the field of pharmaceutical analysis are substantial. His research focus extends to peptide characterization techniques, including Circular Dichroism, Fluorescence Spectrometry, UHPLC-HRMS (Top-down and Bottom-up MS), Dynamic Light Scattering (DLS), SV-AUC, and CE. Additionally, he is well-versed in solid-state characterization techniques such as Particle Size Analysis, PXRD, DSC, and TGA. These techniques are critical in ensuring the quality, efficacy, and safety of pharmaceutical products.His work in method development, validation, and regular analysis using high-performance instruments like HPLC, UPLC, and UHPLC-HRMS has been instrumental in advancing the field of pharmaceutical analysis. Akhilesh’s ability to apply bioinformatics tools for protein mapping and amino acid sequencing further enhances the precision and reliability of his research.

🏆 Accolades and Recognition

Akhilesh’s dedication to excellence in his field is reflected in the numerous certifications and recognitions he has received. In August 2021, he earned Green Belt and Black Belt Certifications in Lean Six Sigma with a Seal of Excellence from Exemplar Global and Benchmark Six Sigma. These certifications demonstrate his commitment to continuous improvement and operational excellence. In September 2021, he furthered his credentials by receiving a Certificate in Excellence in Continuous Improvement Leadership (ECIL) from Benchmark Six Sigma.These accolades not only recognize Akhilesh’s expertise in pharmaceutical analysis but also highlight his leadership abilities in driving efficiency and quality in pharmaceutical research and development.

🌍 Impact and Influence

Akhilesh’s impact on the pharmaceutical industry is profound. His work at Ambiopharm Inc. and previous roles has contributed significantly to the development and validation of methods that ensure the safety and efficacy of pharmaceutical products. His expertise in handling complex regulatory challenges and his ability to troubleshoot analytical methods have made him a valuable asset to his organization and the industry at large.Moreover, Akhilesh’s research in peptide and protein characterization techniques has influenced the way these essential biomolecules are analyzed, leading to more accurate and reliable results. His contributions are particularly important in the context of developing generic peptide products, where precise characterization is critical to ensuring bioequivalence and safety.

👨‍💻 Legacy and Future Contributions

Looking ahead, Akhilesh Kumar Kuril’s legacy in the pharmaceutical industry is poised to grow even further. As he continues to pursue his Ph.D. in Pharmaceutical Analysis from Bhagwant University, Rajasthan, India, Akhilesh is on track to make even more significant contributions to the field. With his thesis already submitted and his graduation anticipated in 2024, Akhilesh’s research and findings are expected to add valuable knowledge to the field of pharmaceutical analysis.Akhilesh’s future contributions will likely focus on advancing analytical techniques and developing innovative methods for drug substance and product characterization. His ongoing commitment to excellence, continuous improvement, and innovation ensures that he will remain at the forefront of the pharmaceutical industry, driving advancements that benefit both the industry and patients worldwide.

Notable Publications 

  • Title: Analytical considerations for characterization of generic peptide product: A regulatory insight
    Authors: Kuril, A.K., Saravanan, K., Subbappa, P.K.
    Journal: Analytical Biochemistry
    Year: 2024.
  • Title: High-throughput method for Peptide mapping and Amino acid sequencing for Calcitonin Salmon in Calcitonin Salmon injection using Ultra High Performance Liquid Chromatography – High Resolution Mass Spectrometry (UHPLC-HRMS) with the application of Bioinformatic tools
    Authors: Kuril, A.K., Saravanan, K.
    Journal: Journal of Pharmaceutical and Biomedical Analysis
    Year: 2024.
  • Title: A comprehensive guide for secondary structure and tertiary structure determination in peptides and proteins by circular dichroism spectrometer
    Authors: Kuril, A.K., Vashi, A., Subbappa, P.K.
    Journal: Journal of Peptide Science
    Year: 2024.
Akhilesh kumar Kuril | Biochemistry | Research Excellence Award

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