Guruvayoorappan C | Cancer | Outstanding Scientist Award

Published-on by Indian Scientist

Dr. Guruvayoorappan C | Cancer | Outstanding Scientist Award

Regional Cancer Centre, Thiruvananthapuram | India

Dr. Guruvayoorappan C is an accomplished Associate Professor at the Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, specializing in cancer biology, immunology, and biotechnology. He holds advanced degrees in Biotechnology, Biochemistry, Botany, and Immunology, with a Ph.D. from Mahatma Gandhi University and postdoctoral research under the UGC Research Award Scheme. With over 20 years of research and 17 years of teaching experience, he has guided several Ph.D. scholars across reputed universities. His extensive contributions include 110 peer-reviewed publications, with 4096 citations, an h-index of 34, and an i10-index of 73, reflecting his impact in oncology and life sciences. His innovative research focuses on cancer immunomodulation, nanomedicine, tumor angiogenesis, and molecular mechanisms of metastasis. He has successfully led multiple government-funded research projects from DBT, ICMR, DST-SERB, and UGC, alongside patents in wound-healing nano scaffolds. Dr. Guruvayoorappan’s work has earned him prestigious honors including the UGC Research Award, DST-Early Career Research Award, ISTE-Periyar Best Teacher Award, and several fellowships from leading scientific academies. His research continues to advance understanding of tumor biology and therapeutic strategies, establishing him as a leading figure in cancer and immunological research.

Profile: Google Scholar

Featured Publications

Aggarwal, B. B., Surh, Y. J., & Shishodia, S. (Eds.). (2007). The molecular targets and therapeutic uses of curcumin in health and disease. Springer Science & Business Media.

Menon, S. S., Guruvayoorappan, C., Sakthivel, K. M., & Rasmi, R. R. (2019). Ki-67 protein as a tumour proliferation marker. Clinica Chimica Acta, 491, 39–45.

Dhanisha, S. S., Guruvayoorappan, C., Drishya, S., & Abeesh, P. (2018). Mucins: Structural diversity, biosynthesis, its role in pathogenesis and as possible therapeutic targets. Critical Reviews in Oncology/Hematology, 122, 98–122.

Rasmi, R. R., Sakthivel, K. M., & Guruvayoorappan, C. (2020). NF-κB inhibitors in treatment and prevention of lung cancer. Biomedicine & Pharmacotherapy, 130, 110569.

Kuttan, G., Hari Kumar, K. B., Guruvayoorappan, C., & Kuttan, R. (2007). Antitumor, anti-invasion, and antimetastatic effects of curcumin. In B. B. Aggarwal, Y. J. Surh, & S. Shishodia (Eds.), The molecular targets and therapeutic uses of curcumin in health and disease (pp. xx–xx). Springer Science & Business Media.

Ruby Anto | Cancer | Best Researcher Award

Published-on by Indian Scientist

Dr. Ruby Anto | Cancer | Best Researcher Award

Centre of Excellence in Nutraceuticals, Government of Kerala | India

Dr. Ruby John Anto is a distinguished biomedical scientist whose pioneering research has significantly advanced the field of cancer biology and nutraceutical sciences. She holds a Ph.D. in Biochemistry from Amala Cancer Research Centre, Thrissur, and has served in various scientific capacities at the Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, including Scientist G, before taking up her current role as Chief Scientist at the Centre of Excellence in Nutraceuticals under KSCSTE, Government of Kerala, and Honorary Scientist at the Institute of Advanced Virology. Her research focuses on the bioprospecting of natural compounds with therapeutic potential against cancer, inflammation, and lifestyle diseases. A highlight of her work is the discovery of Uttroside B, a potent anticancer compound that earned “Orphan Drug” designation from the US FDA for liver cancer treatment and is patented internationally. With an h-index of 42, i10-index of 63, and over 7,600 citations from 80+ international publications, Dr. Anto’s work has received widespread recognition. She has been honored with national and international awards, including the National Woman Bio-Scientist Award and the Keystone Symposia Global Health Award. Her scientific leadership continues to inspire innovation in cancer research, nutraceuticals, and translational medicine.

Profiles: Google Scholar | Scopus

Featured Publications

Ruby, A. J., Kuttan, G., Babu, K. D., Rajasekharan, K. N., & Kuttan, R. (1995). Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Letters, 94(1), 79–83. https://doi.org/ (Cited by: 1571)

Anto, R. J., Mukhopadhyay, A., Denning, K., & Aggarwal, B. B. (2002). Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis, 23(1), 143–150. https://doi.org/ (Cited by: 593)

Anto, R. J., Sukumaran, K., Kuttan, G., Rao, M. N. A., Subbaraju, V., & Kuttan, R. (1995). Anticancer and antioxidant activity of synthetic chalcones and related compounds. Cancer Letters, 97(1), 33–37. https://doi.org/ (Cited by: 456)

Oommen, S., Anto, R. J., Srinivas, G., & Karunagaran, D. (2004). Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells. European Journal of Pharmacology, 485(1–3), 97–103. https://doi.org/ (Cited by: 393)

Anto, R. J., Mukhopadhyay, A., Shishodia, S., Gairola, C. G., & Aggarwal, B. B. (2002). Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκBα: Correlation with induction of cyclooxygenase-2. Carcinogenesis, 23(9), 1511–1518. https://doi.org/ (Cited by: 335)