Early Academic Pursuits :
He embarked on his academic journey with a Bachelor's in Microbiology from Manonmaniam Sundaranar University, followed by a Master of Science in Microbiology from Bangalore University. His zeal for research led him to complete his Ph.D. in Microbiology from Mahatma Gandhi University, Kerala, under the guidance of Dr. V. B Manilal, a distinguished Retd. Chief Scientist.
Professional Endeavors :
With over seven years of post-doctoral research experience in biomedical research, He serves as a Research Associate at the Cancer Biology Division, Rajiv Gandhi Centre for Biotechnology, Trivandrum. His expertise lies in light microscopy and single molecule spectroscopy, focusing on apoptosis-autophagy crosstalk and mitochondrial-ER redox dynamics using various imaging modalities.
Contributions and Research Focus in Genetics and Molecular Biology :
His research concentrates on studying protein-protein interactions in cell-fate decision-making processes using Fluorescence Lifetime (Fast-FLIM) Imaging. He has contributed significantly to the development of genetically encoded cell lines and has conducted high-throughput screening experiments with cancer drugs and compound libraries to assess their impact on cell death processes.
Accolades and Recognition :
His impactful research has earned him prestigious awards and fellowships, including the Best Oral Presentation Award at the Conference on Alternative Animal Research for Translational Research (SAAE-India, 2022). He has been a recipient of various fellowships, including those from the Indian Council for Medical Research and the Kerala State Council for Science Technology and Engineering.
Impact and Influence :
His expertise in light microscopy, drug screening methodologies, and cell biology has enabled him to contribute significantly to understanding mitochondrial and cytosolic redox dynamics, protein-protein interactions, and cell cycle-dependent responses to drug treatments. He has extensively utilized advanced imaging techniques to unravel complex cellular mechanisms.
Legacy and Future Contributions :
His current research focus involves studying slow-progressing changes in redox during cell division, protein-protein interactions, and implications of chronic mitophagy in cancer drug resistance. His dedication to establishing Fast-Fluorescent lifetime Imaging (Fast-FLIM) Facility at RGCB reflects his commitment to advancing research infrastructure. His visionary approach is anticipated to further elevate understanding in cellular biology and aid in the development of targeted cancer therapies.
Notable Publications :