Thanasekaran Ponpandian | Organic Chemistry | Best Researcher Award

Assoc Prof. Dr. Thanasekaran Ponpandian | Organic Chemistry | Best Researcher Award

CSIR-Indian Institute of Chemical Technology, India

Author Profile

Early Academic Pursuits 📚🎓

Dr. Thanasekaran Ponpandian’s academic journey is a testament to his dedication and passion for organic chemistry. He began his educational path with a B.Sc. in Chemistry from V.H.N.S.N. College in Virudhunagar, Tamil Nadu, where he achieved a solid 74.9%. His undergraduate years laid the foundation for his deep interest in the intricacies of chemical processes. Continuing his academic excellence, Dr. Ponpandian pursued an M.Sc. in Chemistry, securing an impressive 79.8% and earning a University II rank at the prestigious V.H.N.S.N. College.

Dr. Ponpandian’s thirst for knowledge and commitment to his field propelled him further into advanced research, culminating in his Ph.D. in Organic Chemistry from Madurai Kamaraj University. His doctoral research, titled “Sequential Reactions in the Synthesis of Heterocyclic Compounds,” was supervised by the esteemed Dr. S. Muthusubramanian. The work focused on developing new methodologies for synthesizing complex heterocyclic structures, which has far-reaching implications in drug discovery and material science. The academic foundation laid in these early years has provided Dr. Ponpandian with the necessary tools to thrive in his professional career.

Professional Endeavors 💼🔬

Dr. Ponpandian’s professional career has been marked by significant contributions to both the pharmaceutical industry and academic research. Currently, he holds the position of Principal Scientist at the CSIR-Indian Institute of Chemical Technology (IICT) in Hyderabad, India, where he specializes in Organic Synthesis and Process Chemistry. His role involves leading cutting-edge research on the synthesis of novel chemical compounds, with applications in drug development and industrial chemistry. At IICT, Dr. Ponpandian continues to push the boundaries of sustainable chemistry and green synthesis.

Before his current position, Dr. Ponpandian played pivotal roles in the R&D divisions of leading pharmaceutical companies such as Mylan Laboratories Ltd. (a Viatris company) and Inogent Laboratories. His work spanned across multiple levels of responsibility, from Deputy Manager to Group Leader and Senior Group Leader, overseeing the development of Active Pharmaceutical Ingredients (APIs) and advancing processes for drug discovery, especially in the oncology therapeutic area. His contributions helped enhance the efficiency and safety of pharmaceutical products, directly impacting public health.

Dr. Ponpandian’s tenure in the pharmaceutical industry, particularly in oncology, has allowed him to work on the design of molecules that could become the backbone of future cancer therapies. His extensive work with drug synthesis and molecular optimization has positioned him as a thought leader in medicinal chemistry.

Contributions and Research Focus 🧬💡

Dr. Ponpandian’s primary research interests are rooted in organic chemistry, with a strong focus on heterocyclic chemistry, catalysis, and the development of new chemical reactions. His research on sequential reactions in heterocyclic compound synthesis has been groundbreaking, leading to the creation of compounds that are essential for pharmaceutical applications. His work on catalysis has opened up new avenues for creating more sustainable and efficient chemical processes, which are crucial for both the pharmaceutical and industrial sectors.

Additionally, Dr. Ponpandian’s research has contributed to the development of green chemistry processes, minimizing waste and improving the sustainability of chemical manufacturing. His efforts to advance drug discovery have had a significant impact on the design of molecules that exhibit therapeutic activity, particularly in oncology and infectious diseases.

Accolades and Recognition 🏆🌟

Throughout his career, Dr. Ponpandian has garnered recognition for his innovative research and leadership in the field of organic chemistry. His work has been published in high-impact journals, contributing significantly to the scientific community. His research contributions have not only advanced sustainable chemistry but have also set new standards for green chemical processes in the industry.

Dr. Ponpandian’s efforts have been acknowledged by his peers, and he continues to be a respected figure in the pharmaceutical and academic circles. His innovative research in drug development has made him a valuable asset in both industry and academia, bridging the gap between theoretical chemistry and practical application.

Impact and Influence 🌍💊

Dr. Ponpandian’s work has had a far-reaching impact on public health through his contributions to the development of new pharmaceutical compounds. His research on drug synthesis has the potential to lead to the creation of life-saving drugs, particularly in the fight against cancer. His commitment to green chemistry and sustainable practices in chemical synthesis has also influenced the way pharmaceutical and chemical industries approach product development, emphasizing the importance of environmentally friendly and cost-effective processes.

Furthermore, Dr. Ponpandian’s academic background and professional experience have allowed him to mentor the next generation of scientists. He continues to inspire young researchers and students, especially those interested in pursuing careers in organic chemistry and drug development.

Legacy and Future Contributions 🔮🌱

Dr. Ponpandian’s legacy will be defined by his contributions to drug discovery, organic synthesis, and sustainable chemistry. His work has already made an indelible mark on the pharmaceutical industry, and he continues to lead cutting-edge research that could transform healthcare worldwide. In the coming years, Dr. Ponpandian aims to continue expanding his research into bioactive compounds, with a particular focus on discovering novel drug candidates for oncological therapies.

Moreover, Dr. Ponpandian is dedicated to fostering innovation in green chemistry and sustainable manufacturing. He envisions a future where chemical synthesis is environmentally sustainable, ensuring that future generations can benefit from both cutting-edge drugs and a cleaner, safer planet.

Dr. Ponpandian’s continued work in organic chemistry promises to shape the future of medicinal chemistry and sustainable industrial practices. His contributions will undoubtedly leave a lasting legacy in both scientific research and the pharmaceutical industry, inspiring new solutions to global health challenges.

Citations

A total of 255 citations for his publications, demonstrating the impact and recognition of his research within the academic community.

  • Citations        255
  • h-index          13
  • i10-index       10

Notable Publications 

  • Title: On Water: Diastereoselective Synthesis of Functionalized 3-Nitrodihydroquinolin-4(1H)-ones Under Catalyst-Free Conditions
    Authors: Peter Raj, A.A., Ponpandian, T.
    Journal: European Journal of Organic Chemistry
    Year: 2024.
  • Title: Silver-Mediated Synthesis of 4H-Benzoxazin-4-ones by Intramolecular Decarboxylative O-Acylation Reactions with α-Oxocarboxylic Acid
    Authors: Bharathimohan, K., Ponpandian, T., Jafar, A.A.
    Journal: European Journal of Organic Chemistry
    Year: 2017.
  • Title: Gold-catalyzed Addition Reaction Between Creatinine and Isatin: A Sustainable and Green Chemistry Approach for the Diastereoselective Synthesis of 3-Substituted-3-Hydroxyisatins
    Authors: Parthasarathy, K., Ponpandian, T., Praveen, C.
    Journal: Cuihua Xuebao/Chinese Journal of Catalysis
    Year: 2017.
  • Title: Orally Available Stilbene Derivatives as Potent HDAC Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts
    Authors: Kachhadia, V., Rajagopal, S., Ponpandian, T., Narayanan, S., Gopalan, B.
    Journal: European Journal of Medicinal Chemistry
    Year: 2016.
  • Title: Sequential Decarboxylative Azide-Alkyne Cycloaddition and Dehydrogenative Coupling Reactions: One-Pot Synthesis of Polycyclic Fused Triazoles
    Authors: Bharathimohan, K., Ponpandian, T., Ahamed, A.J., Bhuvanesh, N.
    Journal: Beilstein Journal of Organic Chemistry
    Year: 2014.

Manisha Bansal | Chemistry | Best Researcher Award

Dr. Manisha Bansal | Chemistry | Best Researcher Award

Punjabi University, Patiala, India

Author Profile

Early Academic Pursuits 🎓

Dr. Manisha Bansal’s academic journey is a testament to her unwavering dedication to the field of medicinal chemistry and bioactive ligand synthesis. Her early fascination with science and research led her to pursue a robust education in chemistry, earning advanced degrees that laid the foundation for her illustrious career. With a strong academic background, she delved deeply into understanding the intricacies of molecular interactions and their implications in medicinal science. Her early exposure to laboratory work fostered a passion for innovation and discovery, setting the stage for a career marked by significant contributions to science.

Professional Endeavors 🏢

Currently serving as an Assistant Professor at Punjabi University, Patiala, Dr. Bansal has become a respected name in medicinal chemistry. Her tenure at the university is marked by a commitment to excellence in teaching, mentoring, and research. Beyond her academic responsibilities, she has been instrumental in establishing a laboratory dedicated to the synthesis of new bioactive ligands. This facility serves as a hub for groundbreaking research and collaboration, nurturing the next generation of scientists. Her work has not only enriched the academic community but has also contributed to the university’s reputation as a center of excellence in research.

Contributions and Research Focus 🧪

Dr. Bansal’s research focuses on the synthesis of novel bioactive ligands derived from medicinally significant small molecules. The primary goal of her research is to explore the structural interactions and chemistry underlying the bioactivity of these ligands. Her laboratory employs advanced techniques such as virtual screening, physicochemical analysis, pharmacokinetic parameter evaluations, and other computational studies to identify and optimize compounds with potential therapeutic benefits.

By investigating how these ligands interact with biological systems, Dr. Bansal has contributed to the understanding of their potential applications in drug discovery and development. Her research has produced valuable insights into the design of more effective and targeted pharmaceutical agents, addressing critical healthcare challenges.

Accolades and Recognition 🏆

Dr. Bansal’s contributions to the scientific community have been widely acknowledged through awards and recognitions. Her innovative research in medicinal chemistry has earned her accolades from national and international organizations. As an author of numerous peer-reviewed publications, she has gained significant recognition in the academic and research communities. Her participation in conferences, workshops, and symposiums has further solidified her position as a thought leader in the field.

Impact and Influence 🌍

Dr. Bansal’s influence extends beyond her immediate academic circle. Her research has implications for both theoretical and applied sciences, bridging the gap between chemistry and pharmacology. By integrating computational methods with experimental studies, she has set a benchmark for interdisciplinary approaches in drug discovery. Her mentorship of students and young researchers has inspired many to pursue careers in medicinal chemistry, amplifying her impact on the field.

Moreover, her work on understanding the bioactivity of ligands is paving the way for advancements in personalized medicine, contributing to more precise and effective treatment options. Her contributions are not limited to academia; they hold the potential to benefit the pharmaceutical industry and improve patient outcomes worldwide.

Legacy and Future Contributions 🌟

Dr. Bansal’s legacy lies in her relentless pursuit of excellence and her ability to inspire and lead in the field of medicinal chemistry. As she continues to explore the fascinating world of bioactive ligands, her future endeavors are likely to yield even more groundbreaking discoveries. Her laboratory is poised to become a hub for innovation, attracting collaborations from across the globe.

Looking ahead, Dr. Bansal aims to expand her research into unexplored areas of ligand synthesis and bioactivity studies. With advancements in computational tools and methodologies, she envisions developing next-generation compounds that address unmet medical needs. Her dedication to mentoring and teaching ensures that her legacy will be carried forward by the many students and researchers who have had the privilege of learning under her guidance.

Conclusion 🌟

Dr. Manisha Bansal exemplifies the qualities of a passionate educator, a pioneering researcher, and a visionary leader. Through her work, she has illuminated the path for future advancements in medicinal chemistry and ligand synthesis. Her contributions, marked by innovation and dedication, will continue to inspire and influence the scientific community for years to come. 🌟✨

Citations

A total of 66 citations for his publications, demonstrating the impact and recognition of his research within the academic community.

  • Citations        66
  • h-index          17
  • i10-index       06

Notable Publications 

  • Comprehensive analysis and outcomes of hybridization of physiologically active heterocycles targeting epidermal growth factor receptor (EGFR)
    Authors: Kaur, M., Rehman, H.M., Wu, Y., Kaur, A., Bansal, M.
    Journal: Computers in Biology and Medicine
    Year: 2025.
  • Synthesis and studies of new purines/pyrimidine derivatives as multi-targeted agents involving various receptor sites in the immune system
    Authors: Kaur, G., Bansal, M., Rehman, H.M., Kaur, M., Kaur, A.
    Journal: Molecular Diversity
    Year: 2024.
  • Investigating multifaceted action of ibuprofen derivatives towards COX isozymes and interleukin-6 (IL-6) site correlating with various target sites
    Authors: Kaur, M., Gupta, P.P., Jain, A., Kaur, A., Bansal, M.
    Journal: Journal of Biomolecular Structure and Dynamics
    Year: 2024.
  • Switching of newly synthesized linker-based derivatives of non-steroidal anti-inflammatory drugs toward anti-inflammatory and anticancer activity
    Authors: Kaur, M., Muzzammel Rehman, H., Kaur, G., Kaur, A., Bansal, M.
    Journal: Bioorganic Chemistry
    Year: 2023.
  • Theoretical molecular predictions and antimicrobial activities of newly synthesized molecular hybrids of norfloxacin and ciprofloxacin
    Authors: Kaur, G., Kaur, M., Sharad, L., Bansal, M.
    Journal: Journal of Heterocyclic Chemistry
    Year: 2020.

Bharath BR | Computational chemistry | Best Researcher Award

Dr. Bharath BR | Computational chemistry | Best Researcher Award

Jai Research Foundation India

Author Profile

Early Academic Pursuits 🎓

Bharath BR’s journey into the world of computational biology began with a robust academic foundation. He pursued an MSc in Bioinformatics from Kuvempu University, Shivamogga, India, graduating in 2008. This laid the groundwork for his interest in bioinformatics and molecular biology. His passion for computational methods in understanding biological systems was solidified when he pursued a Doctor of Philosophy (PhD) from the same institution, which he completed in 2014. His early academic pursuits were focused on understanding molecular modelling and bioinformatics, giving him the skills necessary to delve into complex biological problems using computational tools.During his early academic years, Bharath BR’s interest in systems biology and predictive toxicology grew, leading him to explore the computational aspects of biology. He gained expertise in molecular modelling and simulations, which would later become essential to his professional career. His involvement in academia as a guest lecturer at Kuvempu University shortly after completing his MSc demonstrates his commitment to education and sharing knowledge.

Professional Endeavors 🧑‍🔬

Bharath BR’s career showcases his vast experience in academia and industry, blending both research and application of bioinformatics and computational biology. He began his professional career in academia as an Assistant Professor at the Department of Biotechnology, NMAMIT, Nitte, where he worked from 2010 to 2019. During this period, Bharath contributed significantly to academic teaching and research, with a specific focus on bioinformatics and structural biology. His years in academia allowed him to develop technical expertise, particularly in areas like molecular docking, molecular dynamics, and homology modelling. This experience would later contribute to his research efforts in computational biology.While teaching at NMAMIT, Bharath also built research collaborations with industry partners. His technical consultancy work with Atrimed Biotech LLP in 2017 provided him with industry exposure. His work here involved developing plant molecule databases and performing molecular docking for screening potential plant-based small molecules for therapeutic purposes. As the Head of Computational Biology at Atrimed Biotech LLP from 2019 to 2021, he led a team focused on CADD research (computer-aided drug design), identifying, validating, and modelling potential drug targets.Since 2021, Bharath has been serving as a Senior Research Officer at Jai Research Foundation, India, where he leads the predictive toxicity team. His current role focuses on screening small molecules for various toxicity endpoints and understanding the mechanisms of toxicity through a systems biology approach. Bharath also develops QSAR (Quantitative Structure-Activity Relationship) and statistical models for toxicological endpoints using machine learning techniques. His work contributes to the safety evaluation of molecules, an essential aspect of drug development and chemical safety.

Contributions and Research Focus 🔬

Bharath BR’s research focus spans several cutting-edge fields of computational biology and bioinformatics. Throughout his career, he has developed a broad range of skills that have made him a valuable contributor to various research projects. His expertise includes molecular modelling, molecular docking, epitope mapping, antibody design, and pharmacophore mapping. His proficiency in protein-protein docking, antigen-antibody interactions, and in silico antibody humanisation has allowed him to contribute to research related to drug discovery and molecular interactions.In the realm of predictive toxicology, Bharath has made strides in the prediction and understanding of various toxicological endpoints. His work on skin sensitisation, eye irritation, mutagenicity, and oral toxicity has been instrumental in the preclinical assessment of new compounds. His ability to model and predict the toxicity of molecules using QSAR and PBPK (Physiologically Based Pharmacokinetic) models plays a critical role in reducing the potential risks associated with new chemicals and drugs.Additionally, Bharath’s expertise extends into systems biology, where he uses tools like CellDesigner, Tinker Cell, Cytoscape, and Vcell to model and simulate biological networks. His research into metabolic engineering and flux balance analysis further demonstrates his comprehensive understanding of how biological systems function and how they can be manipulated for therapeutic purposes.

Accolades and Recognition 🏆

Throughout his career, Bharath BR has received recognition for his contributions to the field of computational biology. His technical consultancy work with Atrimed Biotech LLP stands out as a key achievement, where he was able to bridge the gap between academic research and industrial applications. Bharath has been acknowledged for his contributions to the development of plant-based drug discovery, a field that has gained considerable attention due to the potential of plant molecules in therapeutic interventions.His work in predictive toxicology has also garnered attention, particularly his efforts to develop machine learning models for toxicity prediction. Bharath’s contributions have been crucial in enhancing the accuracy of toxicity screening, thereby improving the safety evaluation of drugs and chemicals.

Impact and Influence 🌍

Bharath’s work in computational biology has had a significant impact on both academic research and industrial applications. By integrating bioinformatics with predictive toxicology and systems biology, he has influenced the way researchers approach drug discovery and toxicity evaluation. His contributions to the development of machine learning models for predicting toxicological endpoints have advanced the ability to screen compounds more efficiently, reducing the reliance on animal testing and accelerating the drug development process.Furthermore, Bharath’s academic background and teaching experience have allowed him to influence a new generation of bioinformatics students and researchers. His work as an educator and mentor has helped shape the future of computational biology research.

Legacy and Future Contributions 🌟

Looking ahead, Bharath BR’s legacy will likely be defined by his contributions to computational biology, particularly his work in the areas of predictive toxicology and drug discovery. His ongoing research in developing more accurate and efficient computational models will continue to shape the fields of toxicology, systems biology, and bioinformatics.Bharath’s future contributions are poised to have a lasting impact on the pharmaceutical and biotechnology industries, where his work on predictive models and in silico methods can lead to safer and more effective therapies. His unique combination of academic expertise and industrial experience positions him to make significant advances in the field of computational biology.

Citations

A total of 304 citations for his publications, demonstrating the impact and recognition of his research within the academic community.

  • Citations         304
  • h-index           21
  • i10-index        9

Notable Publications 

  • Title: Plant formulation ATRICOV 452 in improving the level of COVID-19 specific inflammatory markers in patients
    Authors: Damle, L., Damle, H., BR, B.
    Journal: Contemporary Clinical Trials Communications
    Year: 2022.
  • Title: In silico, in vitro screening of plant extracts for anti-SARS-CoV-2 activity and evaluation of their acute and sub-acute toxicity
    Authors: Latha, D., Hrishikesh, D., Shiban, G., Chandrashekar, C., Bharath, B.R.
    Journal: Phytomedicine Plus
    Year: 2022.
  • Title: Understanding pharmacodynamics of butyl isobutyl phthalate: Where in vitro and in silico studies converge
    Authors: Raghavendra, H.L., Bharath, B.R., Kekuda, T.R.P., Chaitanya, M.M.V.N.L., Kumar, H.S.S.
    Journal: Indian Journal of Pharmaceutical Sciences
    Year: 2021.
  • Title: Protein-protein interaction and molecular dynamics of iturin a gene on effector proteins of phytophthora infestans
    Authors: Kumbar, B., Kandagalla, S., Bharath, B.R., Sharath, B.S., Mahmood, R.
    Journal: Combinatorial Chemistry and High Throughput Screening
    Year: 2021.
  • Title: Stable isoniazid derivatives: In silico studies, synthesis and biological assessment against mycobacterium tuberculosis in liquid culture
    Authors: Gaonkar, S.L., Hakkimane, S.S., Bharath, B.R., Vignesh, U.N., Guru, B.R.
    Journal: Rasayan Journal of Chemistry
    Year: 2020.