Early Academic Pursuits

She embarked on her academic journey with a profound interest in Chemistry. Graduating with a Bachelor of Science degree in Chemistry from Calicut University, where she secured the second rank in the university, demonstrated her early aptitude and dedication to the field. She continued her academic pursuits by obtaining a Master of Science degree in Chemistry from Mahatma Gandhi University, specializing in Organic Chemistry, and graduating with distinction and the first position. These early academic achievements laid the foundation for her subsequent research endeavors.

Professional Endeavors

She furthered her academic pursuits by pursuing a Ph.D. in Inorganic Chemistry at Cochin University of Science and Technology (CUSAT). Her doctoral research focused on the synthesis and characterization of Copper(II) complexes based on halogen-substituted carbonyl compounds. Her thesis, titled "Crystalline architectures of Copper (II) complexes based on halogen substituted carbonyl compounds: Interplay of covalent and non-covalent forces," delved into the synthesis of Schiff bases and their Cu(II) complexes, their crystallization, and characterization using various techniques such as UV-Vis, IR, SXRD, NMR, TG-DTA/DSC, and EPR. The relevance of these complexes in biomimetic activity, enzyme catalysis, and binding studies with DNA was also highlighted.

Contributions and Research Focus in Computational Drug Discovery

Her research focus spans across Computational Drug Discovery, Molecular Docking, Virtual Screening, Molecular Dynamics Simulation, and Ligand-Based Drug Design. Her doctoral and post-doctoral research projects have contributed significantly to these areas, particularly in the development and application of computational methods for drug discovery. Her work on the synthesis and characterization of metal complexes and their relevance in biomimetic activity and binding studies has laid the groundwork for her current research endeavors in computational drug discovery.

Accolades and Recognition

She has been recognized for her academic and research excellence through various awards and fellowships. She was awarded the prestigious D.S. Kothari post-doctoral fellowship and received the CSIR/UGC fellowship for her Ph.D. Additionally, her outstanding academic performance, including securing the first position in M.Sc. Chemistry and the second rank in B.Sc. Chemistry, has been acknowledged by her academic institutions.

Impact and Influence

Her research has the potential to have a significant impact on the field of drug discovery. Her contributions to Computational Drug Discovery, Molecular Docking, Virtual Screening, Molecular Dynamics Simulation, and Ligand-Based Drug Design have implications for the development of novel therapeutic agents for various diseases, including epilepsy. Her interdisciplinary approach, combining expertise in chemistry and computational methods, positions her as a valuable asset in the field of drug discovery.

Legacy and Future Contributions

Notable Publications

• Inclusion, pseudo-inclusion compounds and coordination polymer of Pd (II), Zn (II) and Cd (II) from salen-type Schiff base ligand with a 1, 3-diimino spacer group: Crystal …
• The ligating versatility of pseudohalides like thiocyanate and cyanate in copper (II) complexes of 2-benzoylpyridine semicarbazone: Monomer, dimer and polymer
• Polymeric polymorphs and a monomer of pseudohalide incorporated Cu (II) complexes of 2, 4-dichlorido-6-((2-(dimethylamino) ethylimino) methyl) phenol]: Crystal structures and …
• Synthesis and spectral characterization of mono-and binuclear copper (II) complexes derived from 2-benzoylpyridine-N4-methyl-3-thiosemicarbazone: Crystal structure of a novel …
• Self-organized three dimensional architectures based on non-covalent interactions in square planar Cu (II) thiosemicarbazone: Solvent mediated crystallization and EPR based …
• Screening of FDA-approved compound library identifies potential small-molecule inhibitors of SARS-CoV-2 non-structural proteins NSP1, NSP4, NSP6 and NSP13: molecular modeling …
• NHC-catalyzed annulation of enals and chalcones: further explorations on the novel synthesis of 1, 3, 4-trisubstituted cyclopentenes
• N′-[(E)-2-Fluorobenzylidene] benzohydrazide
• Methods and applications of machine learning in structure-based drug discovery
• Crystal structure of (E)-N′-(5-bromo-2-hydroxybenzylidene) nicotinohydrazide monohydrate
• Dichlorido {2-[(E)-phenyl (pyridin-2-yl-κN) methylidene]-N-phenylhydrazinecarboxamide-κ2N2, O} copper (II)
• N′-[(1E)-1-(2-Fluorophenyl) ethylidene] pyridine-3-carbohydrazide