Koneru Lakshmaiah Education Foundation - India🏆
Professional Profiles:
Early Academic Pursuits :
His academic journey began with a focus on DNA structural analysis and its implications in gene expression during the early years of his research career. Exploring the intricacies of eukaryotic and prokaryotic DNA, he demonstrated a keen interest in understanding core promoter regions and DNA motifs, paving the way for significant contributions in deciphering the structural aspects of DNA and their functional roles.
Professional Endeavors :
His professional career evolved around interdisciplinary research, blending bioinformatics, computational biology, and molecular biology. His tenure at K L University since 2016 has been instrumental in fostering an environment conducive to cutting-edge research in genomics, structural biology, and computational genomics.
Contributions and Research Focus in Computational Biology:
His research has made substantial contributions to the understanding of DNA structural features influencing gene regulation, transcription factor binding, and the role of DNA motifs in gene expression. His work on G-quadruplexes, DNA flexibility, and the impact of DNA sequence environments on transcription factor affinity has significantly advanced the field's understanding of genome organization and gene responsiveness.
His expertise in employing deep learning and machine learning techniques to analyze biological data has been pivotal in unveiling hidden patterns within DNA sequences and regulatory regions across various organisms, establishing connections between structural elements and functional outcomes.
Accolades and Recognition :
His contributions have garnered substantial recognition, evident from his prolific publication record and high citation count. With an impressive H-index of 7 and a total of 18 citations for 15 publications within the specified timeframe, His work has been widely acknowledged and cited in prominent journals, reflecting its impact and significance within the scientific community.
Impact and Influence :
His studies have greatly influenced the fields of genomics, bioinformatics, and computational biology by providing critical insights into the structural determinants governing gene regulation. His research findings have laid a foundation for further investigations into DNA-protein interactions, regulatory mechanisms, and the development of predictive models for gene expression and transcriptional control.
Legacy and Future Contributions :
His legacy lies in his pioneering contributions to understanding DNA structure-function relationships and their implications in gene expression. His multidisciplinary approach integrating computational techniques with molecular biology has set a benchmark for future research in deciphering complex genomic landscapes.
Notable Publications :
- Computational analysis on the dissemination of non-B DNA structural motifs in promoter regions of 1180 cellular genomes
- DNA structural properties of DNA binding sites for 21 transcription factors in the mycobacterial genome.
- Raw sequence and Non-B-DNA occurrence datasets
- Nucleic acid-based therapeutics for dermal wound healing
- Evolution of machine learning in biosciences: A bibliometric network analysis