Dr. RAGHU K G | Pharmacology | Best Researcher Award
JUBILEE MISSION MEDICAL COLLEGE AND RESEARCH INSTITUTE,THRISSUR-India
Author Profile
Early Academic Pursuits 📚
Dr. K.G. Raghu’s journey in scientific research began with a strong academic foundation in the life sciences. He completed his Bachelor’s degree in Zoology, Botany, and Chemistry from Calicut University in 1983, achieving first-class honors. His passion for understanding biological systems led him to pursue a Master’s degree in Zoology from the same university, graduating in 1985 with first-class distinction.Dr. Raghu’s pursuit of knowledge continued with a Ph.D. from Saurashtra University, where his research focused on the effects of organomercurials pollution on the biochemical changes in the central nervous system of rats. His dissertation, titled “Effect of Organomercurials Pollution in Animals: Evaluation of Biochemical Changes in the Central Nervous System of Rat with Methylmercury and Chelators,” was completed under the supervision of Prof. P. P. Sood. This early work laid a solid groundwork for his future research in neurotoxicology and pharmacology.Following his Ph.D., Dr. Raghu undertook post-doctoral research at the Department of Biotechnology, Cochin University of Science & Technology. His research, supervised by Dr. C.S. Paulose, focused on neurotransmitter-receptor functions in mercury poisoning and the effects of chitosan.
Professional Endeavors 🔬
Dr. Raghu’s professional career is marked by significant contributions to the field of pharmacology and drug development, particularly in cardiovascular disease (CVD) and metabolic syndrome. His career began at the CSIR Central Drug Research Institute, Lucknow, where he served in various capacities from Scientist B to Senior Scientist between 1995 and 2008. His work focused on drug development for cardiovascular diseases and safety pharmacology, which helped advance therapeutic approaches in this critical area.In 2008, Dr. Raghu joined the CSIR-National Institute for Interdisciplinary Science & Technology (NIIST), Trivandrum, where he made remarkable contributions as a Senior Scientist, Principal Scientist, and eventually Senior Principal Scientist. His research during this period centered on the basic biology of metabolic syndromes and bioactives. He led pioneering studies on the development of leads for metabolic syndrome and explored bioactive compounds with therapeutic potential.In 2021, Dr. Raghu retired as Chief Scientist from NIIST but continued his impactful work as an Honorary Scientist at the Jubilee Mission Medical College & Research Institute, Trichur, Kerala. His research continues to address the fundamental biology of metabolic syndromes, further demonstrating his dedication to advancing medical science.
Contributions and Research Focus 🧬
Dr. Raghu’s research has had a profound impact on the understanding and treatment of metabolic syndromes and cardiovascular diseases. His studies have explored the biochemical mechanisms underlying these conditions and developed potential therapeutic leads. Notable contributions include:
- Drug Development for Cardiovascular Diseases: Dr. Raghu’s early work involved developing and testing new drugs for cardiovascular conditions, focusing on safety pharmacology.
- Metabolic Syndrome Research: His later research at NIIST was groundbreaking in exploring the basic biology of metabolic syndromes and developing bioactive compounds to combat these disorders. His work on compounds from natural sources has been particularly influential in identifying potential new treatments.
Dr. Raghu has also been instrumental in supervising Ph.D. and post-doctoral research, guiding several students and researchers in their scientific careers. His mentorship has led to significant advancements in the understanding of oxidative stress, cardiac hypertrophy, and metabolic syndrome.
Accolades and Recognition 🏆
Dr. Raghu’s contributions have been widely recognized in the scientific community. His work has not only advanced the field of pharmacology but has also earned him a place among the leading researchers in metabolic syndrome and cardiovascular diseases. He is a Fellow of the Indian Academy of Biomedical Sciences and the Kerala Academy of Sciences, highlighting his prominence and influence in the field.
Impact and Influence 🌍
Dr. Raghu’s research has had a lasting impact on the scientific understanding of cardiovascular and metabolic diseases. His innovative approaches and discoveries have paved the way for new therapeutic strategies and drug developments. His role as a mentor and guide to numerous researchers has further amplified his influence, fostering a new generation of scientists dedicated to advancing medical research.
Legacy and Future Contributions 🔮
As Dr. Raghu continues his work as an Honorary Scientist at the Jubilee Mission Medical College & Research Institute, his legacy is characterized by a commitment to advancing scientific knowledge and improving human health. His ongoing research aims to unravel further complexities of metabolic syndromes and develop effective interventions.Dr. Raghu’s career serves as an inspiring example of how dedication to research and mentoring can lead to significant advancements in science and medicine. His work not only contributes to the current understanding of critical health issues but also sets the stage for future breakthroughs in the field.
Citations
A total of 2610 citations for his publications, demonstrating the impact and recognition of his research within the academic community.
- Citations 2610
- h-index 102
- i10-index 31
Notable Publications
- Title: Joubert syndrome causing mutation in C2 domain of CC2D2A affects structural integrity of cilia and cellular signaling molecules
Authors: Jayarajan, R.O., Chakraborty, S., Raghu, K.G., Purushothaman, J., Veleri, S.
Journal: Experimental Brain Research
Year: 2024. - Title: Corrosion and in vitro characteristics of cerium phosphate based chemical conversion coating on AZ31 magnesium alloy
Authors: Jayaraj, J., Kumar, S.A., Srinivasan, A., Arunchandran, C., Rajinikanth, V.
Journal: Applied Surface Science
Year: 2024. - Title: A clinically feasible diagnostic spectro-histology built on SERS-nanotags for multiplex detection and grading of breast cancer biomarkers
Authors: Murali, V.P., Karunakaran, V., Murali, M., Sujathan, K., Maiti, K.K.
Journal: Biosensors and Bioelectronics
Year: 2023. - Title: Vanillic acid mitigates hyperinsulinemia induced ER stress mediated altered calcium homeostasis, MAMs distortion and surplus lipogenesis in HepG2 cells
Authors: Mohan, S., Nair, A., Poornima, M.S., Raghu, K.G.
Journal: Chemico-Biological Interactions
Year: 2023. - Title: In vitro and in vivo anti-inflammatory and anti-arthritic effect of Tinospora cordifolia via modulation of JAK/STAT pathway
Authors: George, G., Shyni, G.L., Mohan, S., Rajankutty, K., Raghu, K.G.
Journal: Inflammopharmacology
Year: 2023.